Examining the functional activity of different obsessive-compulsive symptom dimensions in Tourette syndrome.

ABSTRACT:

Objectives

Tourette syndrome (TS) is commonly comorbid with obsessive-compulsive disorder (OCD) and many phenomenological similarities exist between tics and obsessive-compulsive symptoms (OCS). Therefore, due to the clinical importance of comorbid OCD, the goal of this study was to investigate the neural substrates of OCS in TS using functional magnetic resonance imaging.

Methods

Forty patients with TS and 20 healthy controls underwent functional magnetic resonance imaging while viewing blocks of OCS-provoking pictures relating to washing, checking and symmetry symptoms, as well as generally disgusting and neutral scenes. Statistical comparisons were made between patients with moderate/severe OCS, absent/mild OCS and healthy controls. As well, within the entire TS patient g

SUBMITTER: Bhikram T 

PROVIDER: S-EPMC7025096 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature