Acute kidney injury calculated using admission serum creatinine underestimates 30-day and 1-year mortality after acute stroke.

ABSTRACT:

Background

Acute kidney injury (AKI) diagnosis requires ascertainment of change from a known baseline. Although pre-admission serum creatinine (SCr) is recommended, to date, all studies of AKI in acute stroke have used the first SCr on admission.

Methods

All patients admitted with an acute stroke to an emergency hospital were recruited. We compared use of pre-admission SCr with admission SCr to diagnose AKI. Regression analyses were used to identify risk factors for 30-day and 1-year mortality, respectively.

Results

A total of 1354 patients were recruited from December 2012 to September 2015. Incidence of AKI was 18.7 and 19.9% using pre-admission SCr and admission SCr, respectively. Diagnosis of AKI was associated with significantly increased 30-day and 1-year mortal

SUBMITTER: Arnold J 

PROVIDER: S-EPMC7025354 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature