First case report of cutaneous sporotrichosis (Sporothrix species) in a cat in the UK.

ABSTRACT:

Case summary

A 12-year-old female neutered indoor-outdoor domestic longhair cat presented with frequent sneezing and a nodular, suppurative lesion on its dorsal nose. Histopathological examination revealed a fungal granuloma. PCR and sequencing of the ribosomal internal transcribed spacers (ITS) regions (ITS-F and ITS-R) confirmed an infection with a Sporothrix species. Further sequencing of the beta-tubulin and calmodulin genes confirmed Sporothrix humicola, which lies within the Sporothrix pallida complex. The cat had concurrent diabetes mellitus, which responded to insulin therapy and diet. Oral itraconazole at 10 mg/kg PO q24h resulted in resolution of the lesions after 12 months. Treatment was well tolerated.

Relevance and novel information

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SUBMITTER: Makri N 

PROVIDER: S-EPMC7025424 | biostudies-literature | 2020 Jan-Jun

REPOSITORIES: biostudies-literature