Circadian and Genetic Modulation of Visually-Guided Navigation in Drosophila Larvae.

ABSTRACT: Organisms possess an endogenous molecular clock which enables them to adapt to environmental rhythms and to synchronize their metabolism and behavior accordingly. Circadian rhythms govern daily oscillations in numerous physiological processes, and the underlying molecular components have been extensively described from fruit flies to mammals. Drosophila larvae have relatively simple nervous system compared to their adult counterparts, yet they both share a homologous molecular clock with mammals, governed by interlocking transcriptional feedback loops with highly conserved constituents. Larvae exhibit a robust light avoidance behavior, presumably enabling them to avoid predators and desiccation, and DNA-damage by exposure to ultraviolet light, hence are crucial for survival. Circadian rhyt

SUBMITTER: Asirim EZ 

PROVIDER: S-EPMC7026142 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature