Retrospective Screening and Analysis of mcr-1 and bla _NDM in Gram-Negative Bacteria in China, 2010-2019.

ABSTRACT: Currently, Gram-negative bacteria have developed multidrug and broad-spectrum drug resistance, and the numbers of species and strains carrying mcr or bla _NDM genes are increasing. In this study, mcr-1 and bla _NDM distribution of 12,858 Gram-negative bacteria isolated from wildlife, patients, livestock, poultry and environment in 14 provinces of China from 2010 to 2019 and the antibiotics resistance in regard to polymyxins (polymyxin B and colistin) and carbapenems of positive strains were investigated. A total of 70 strains of 10 species carried the mcr-1 gene, positive rates of patients, livestock and poultry, and environmental strains were 0.62% (36/5,828), 4.07% (29/712), 5.43% (5/92), respectively. Six strains of 3 species carryi

SUBMITTER: Fan R 

PROVIDER: S-EPMC7026248 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature