Prevalence of steatosis and fibrosis in young adults in the UK: a population-based study.

ABSTRACT:

Background

The estimated worldwide prevalence of non-alcoholic fatty liver disease (NAFLD) in adults is 25%; however, prevalence in young adults remains unclear. We aimed to identify the prevalence of steatosis and fibrosis in young adults in a sample of participants recruited through the Avon Longitudinal Study of Parents and Children (ALSPAC), based on transient elastography and controlled attenuation parameter (CAP) score.

Methods

In this population-based study, we invited active participants of the ALSPAC cohort to our Focus@24+ clinic at the University of Bristol (Bristol, UK) between June 5, 2015, and Oct 31, 2017, for assessment by transient elastography with FibroScan, to determine the prevalence of steatosis and fibrosis. FibroScan data were collected on histologica

SUBMITTER: Abeysekera KWM 

PROVIDER: S-EPMC7026693 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature