The role of prescription drugs in female overactive bladder syndrome-A population-wide cohort study.

ABSTRACT:

Purpose

Overactive bladder (OAB) syndrome has severe effects on quality of life. Certain drugs are known risk factors for OAB but have not been investigated in a population-wide cohort. The objective of this study was to investigate the role of prescription drugs in the etiology of the OAB.

Methods

Retrospective cohort study using a population-wide database of 4 185 098 OAB-naïve women followed Strengthening the Reporting of Observational Studies in Epidemiology guidelines. We investigated the subscription use of anticholinergic medication and 188 chemical substances, which are suspected triggers for OAB (trigger medications [TMs]). We hypothesized a relationship between the prescription for one or more TM and the prescription for anticholinergic medication against OAB (mark

SUBMITTER: Umek W 

PROVIDER: S-EPMC7027558 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature