Coping with interfraction time trends in tumor setup.

ABSTRACT: PURPOSE:Interfraction tumor setup variations in radiotherapy are often reduced with image guidance procedures. Clinical target volume (CTV)-planning target volume (PTV) margins are then used to deal with residual errors. We have investigated characterization of setup errors in patient populations with explicit modelling of occurring interfraction time trends. METHODS:The core of a "trendline characterization" of observed setup errors in a population is a distribution of trendlines, each obtained by fitting a straight line through a patient's daily setup errors. Random errors are defined as daily deviations from the trendline. Monte Carlo simulations were performed to predict the impact of offline setup correction protocols on residual setup errors in patient populations with time trends. A

SUBMITTER: Gizynska MK 

PROVIDER: S-EPMC7027586 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature