Design and analysis considerations for cohort stepped wedge cluster randomized trials with a decay correlation structure.

ABSTRACT: A stepped wedge cluster randomized trial is a type of longitudinal cluster design that sequentially switches clusters to intervention over time until all clusters are treated. While the traditional posttest-only parallel design requires adjustment for a single intraclass correlation coefficient, the stepped wedge design allows multiple outcome measurements from the same cluster and so additional correlation parameters are necessary to characterize the within-cluster correlation structure. Although a number of studies have differentiated between the concepts of within-period and between-period correlations, only a few studies have allowed the between-period correlation to decay over time. In this article, we consider the proportional decay correlation structure for a cohort stepped wedge de

SUBMITTER: Li F 

PROVIDER: S-EPMC7027591 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature