Light to moderate amount of lifetime alcohol consumption and risk of cancer in Japan.

ABSTRACT: BACKGROUND:Even light to moderate alcohol consumption has been shown to increase cancer incidence. However, this association has not been well characterized in Japan. METHODS:Based on a nationwide, hospital-based data set (2005-2016), a multicenter case-control study was conducted (63,232 cancer cases and 63,232 controls matched for sex, age, admission date, and admitting hospital). The total amount of lifetime alcohol consumption (drink-years) was recalled for each patient by multiplication of the daily amount of standardized alcohol use (drinks per day) and the duration of drinking (years). Odds ratios (ORs) were estimated for overall and specific cancer sites via conditional logistic regression with restricted cubic splines, with adjustments made for smoking, occupational class, and com

SUBMITTER: Zaitsu M 

PROVIDER: S-EPMC7027900 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature