Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database.

ABSTRACT: OBJECTIVE:To explore the effect of initiating statins for secondary prevention after a first myocardial infarction (MI) in patients aged 80 years and older. DESIGN:Retrospective cohort study. SETTING:Clinical Practice Research Datalink (1999-2016). PARTICIPANTS:Patients, aged 65 years and older, hospitalized after a first MI without a statin prescription in the year before hospitalization. The age group of 65 to 80 years was included to compare our results to current evidence. MEASUREMENTS:The primary outcome was a composite of recurrent MI, stroke, and cardiovascular mortality; and the secondary outcome was all-cause mortality. A time-varying Cox model was used to account for statin prescription over time. We compared at least 2 years of statin prescription time with untreated and less th

SUBMITTER: Lefeber GJ 

PROVIDER: S-EPMC7028025 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature