National U.S. time-trends in opioid use disorder hospitalizations and associated healthcare utilization and mortality.

ABSTRACT: BACKGROUND:The opioid epidemic is a major public health crisis in the U.S. Contemporary data on opioid use disorder (OUD) related hospitalizations are needed. Our objective was to assess whether OUD hospitalizations and associated mortality are increasing over time and examine the factors associated healthcare utilization and mortality. METHODS AND FINDINGS:We examined the rates of OUD hospitalizations and associated mortality using the U.S. National Inpatient Sample (NIS) data from 1998-2016. Multivariable-adjusted logistic regression assessed the association of demographic, clinical and hospital characteristics with inpatient mortality and healthcare utilization (total hospital charges, discharge to a rehabilitation facility, length of hospital stay) during the index hospitalization for

SUBMITTER: Singh JA 

PROVIDER: S-EPMC7028263 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature