Iron status and risk factors for iron depletion in a racially/ethnically diverse blood donor population.

ABSTRACT:

Background

The optimal approach for reducing iron depletion (ID) in blood donors may vary depending on biologic or behavioral differences across donors.

Study design and methods

More than 12,600 successful whole blood donors were enrolled from four US blood centers for ferritin testing. The study population was enriched for racial/ethnic minorities (1605 African American, 1616 Asian, 1023 Hispanic). Subjects completed questionnaires on ID risk factors. Logistic regression identified predictors of absent iron stores (AIS; ferritin <12 ng/mL) and low ferritin (LF; ferritin <26 ng/mL).

Results

Across all subjects, 19% had AIS and 42% had LF, with a sharp increase in risk observed with increasing donation intensity and among women a large decrease in risk in those more th

SUBMITTER: Spencer BR 

PROVIDER: S-EPMC7028389 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature