Gastrointestinal symptoms are associated with trajectories of chemotherapy-induced nausea.

ABSTRACT:

Purpose

Between 19 and 58% of oncology patients experience chemotherapy-induced nausea (CIN). In a sample of outpatients with breast, gastrointestinal (GI), gynecological, and lung cancer, the study purposes were to evaluate for inter-individual differences in the severity of CIN over two cycles of chemotherapy (CTX) and to determine which demographic and clinical characteristics and GI symptoms were associated with higher initial levels as well as with the trajectories of CIN severity.

Methods

Patients completed study questionnaires at six time points over two cycles of CTX. These questionnaires provided information on demographic and clinical characteristics, as well as the occurrence of twelve GI symptoms. Hierarchical linear modeling based on full maximum likelihood esti

SUBMITTER: Singh K 

PROVIDER: S-EPMC7028490 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature