Characterizing health state utilities associated with Duchenne muscular dystrophy: a systematic review.

ABSTRACT:

Background

Preferences for health states for Duchenne muscular dystrophy (DMD) are necessary to assess costs and benefits of novel therapies. Because DMD progression begins in childhood, the impact of DMD on health-related quality-of-life (HRQoL) affects preferences of both DMD patients and their families. The objective of this review was to synthesize published evidence for health state utility from the DMD patient and caregiver perspectives.

Methods

A systematic review was performed using MEDLINE and Embase, according to best practices. Data were extracted from studies reporting DMD patient or caregiver utilities; these included study and patient characteristics, health states considered, and utility estimates. Quality appraisal of studies was performed.

Results

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SUBMITTER: Szabo SM 

PROVIDER: S-EPMC7028804 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature