Genomic scan of selective sweeps in Djallonke (West African Dwarf) sheep shed light on adaptation to harsh environments.

ABSTRACT: The Djallonké (West African Dwarf) sheep is a small-sized haired sheep resulting from a costly evolutionary process of natural adaptation to the harsh environment of West Africa including trypanosome challenge. However, genomic studies carried out in this sheep are scant. In this research, genomic data of 184 Djallonké sheep (and 12 Burkina-Sahel sheep as an outgroup) generated using medium-density SNP Chips were analyzed. Three different statistics (iHS, XP-EHH and nSL) were applied to identify candidate selection sweep regions spanning genes putatively associated with adaptation of sheep to the West African environment. A total of 207 candidate selection sweep regions were defined. Gene-annotation enrichment and functional annotation analyses allowed to identify three statistically signi

SUBMITTER: Alvarez I 

PROVIDER: S-EPMC7028950 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature