Eczema phenotypes and risk of allergic and respiratory conditions in school age children.

ABSTRACT:

Background

Eczema phenotypes based on eczema onset and persistence might better identify groups prone to allergic and respiratory conditions than a binary definition of eczema. We examined the associations of childhood eczema phenotypes with allergic sensitization, allergy, asthma and lung function at school age.

Methods

This study among 4277 children was embedded in a multi-ethnic population-based prospective cohort study. Five eczema phenotypes (never, early transient, mid-transient, late transient, persistent) based on parental-reported physician-diagnosed eczema from age 6 months until 10 years were identified. At age 10 years, allergic sensitization was measured by skin prick tests, physician-diagnosed allergy and asthma by parent-reported questionnaires, and lung funct

SUBMITTER: Hu C 

PROVIDER: S-EPMC7029507 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature