Neural and Psychological Predictors of Cognitive Enhancement and Impairment from Neurostimulation.

ABSTRACT: Modulating the temporoparietal junction (TPJ), especially the right counterpart, shows promises in enhancing social cognitive ability. However, it is ambiguous whether the functional lateralization of TPJ determines people's responsiveness to brain stimulation. Here, this issue is investigated with an individual difference approach. Forty-five participants attended three sessions of transcranial direct current stimulation (tDCS) experiments and one neuroimaging session. The results support the symmetric mechanism of left and right TPJ stimulation. First, the left and right TPJ stimulation effect are comparable in the group-level analysis. Second, the individual-level analysis reveals that a less right-lateralized TPJ is associated with a higher level of responsiveness. Participants could b

SUBMITTER: Yang LZ 

PROVIDER: S-EPMC7029648 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature