The Graded Change in Connectivity across the Ventromedial Prefrontal Cortex Reveals Distinct Subregions.

ABSTRACT: The functional heterogeneity of the ventromedial prefrontal cortex (vmPFC) suggests it may include distinct functional subregions. To date these have not been well elucidated. Regions with differentiable connectivity (and as a result likely dissociable functions) may be identified using emergent data-driven approaches. However, prior parcellations of the vmPFC have only considered hard splits between distinct regions, although both hard and graded connectivity changes may exist. Here we determine the full pattern of change in structural and functional connectivity across the vmPFC for the first time and extract core distinct regions. Both structural and functional connectivity varied along a dorsomedial to ventrolateral axis from relatively dorsal medial wall regions to relatively lateral

SUBMITTER: Jackson RL 

PROVIDER: S-EPMC7029692 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature