Association of Sex With Outcomes in Patients Undergoing Percutaneous Coronary Intervention: A Subgroup Analysis of the GLOBAL LEADERS Randomized Clinical Trial.

ABSTRACT:

Importance

Women experience worse ischemic and bleeding outcomes after percutaneous coronary intervention (PCI).

Objectives

To assess the association of sex with patient outcomes at 2 years after contemporary PCI and with the efficacy and safety of 2 antiplatelet strategies.

Design, setting, and participants

This study is a prespecified subgroup analysis of the investigator-initiated, prospective, randomized GLOBAL LEADERS study evaluating 2 strategies of antiplatelet therapy after PCI in an unselected population including 130 secondary/tertiary care hospitals in different countries. The main study enrolled 15 991 unselected patients undergoing PCI between July 2013 and November 2015. Patients had an outpatient clinic visit at 30 days and 3, 6, 12, 18, and 24 months a

SUBMITTER: Chichareon P 

PROVIDER: S-EPMC7029729 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature