Androgen deprivation therapy for prostate cancer and the risk of hematologic disorders.

ABSTRACT: PURPOSE:This study aimed to investigate the association between androgen deprivation therapy (ADT) and the risk of subsequently developing hematologic disorders in patients with prostate cancer. MATERIALS AND METHODS:This population-based nationwide cohort study utilized data from the Taiwan National Health Insurance Research Database between 1997 and 2013. The patients were divided into three groups-those who received ADT only (ADT-only group), those who had radiotherapy (RT) only (RT-only group), and those treated with radical prostatectomy (RP) only (RP-only group). The study outcome was newly diagnosed hematologic disorder, including anemia and hematologic malignancy. Propensity score-matched, Cox regression, and Kaplan-Meier curve analyses were performed to investigate the risk of sub

SUBMITTER: Liu JM 

PROVIDER: S-EPMC7029847 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature