Interplay between competitive and cooperative interactions in a three-player pathogen system.

ABSTRACT: In ecological systems, heterogeneous interactions between pathogens take place simultaneously. This occurs, for instance, when two pathogens cooperate, while at the same time, multiple strains of these pathogens co-circulate and compete. Notable examples include the cooperation of human immunodeficiency virus with antibiotic-resistant and susceptible strains of tuberculosis or some respiratory infections with Streptococcus pneumoniae strains. Models focusing on competition or cooperation separately fail to describe how these concurrent interactions shape the epidemiology of such diseases. We studied this problem considering two cooperating pathogens, where one pathogen is further structured in two strains. The spreading follows a susceptible-infected-susceptible process and the stra

SUBMITTER: Pinotti F 

PROVIDER: S-EPMC7029927 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature