Corticomuscular control of walking in older people and people with Parkinson's disease.

ABSTRACT: Changes in human gait resulting from ageing or neurodegenerative diseases are multifactorial. Here we assess the effects of age and Parkinson's disease (PD) on corticospinal activity recorded during treadmill and overground walking. Electroencephalography (EEG) from 10 electrodes and electromyography (EMG) from bilateral tibialis anterior muscles were acquired from 22 healthy young, 24 healthy older and 20 adults with PD. Event-related power, corticomuscular coherence (CMC) and inter-trial coherence were assessed for EEG from bilateral sensorimotor cortices and EMG during the double-support phase of the gait cycle. CMC and EMG power at low beta frequencies (13-21 Hz) was significantly decreased in older and PD participants compared to young people, but there was no difference between older

SUBMITTER: Roeder L 

PROVIDER: S-EPMC7031238 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature