Genome-wide association mapping for dominance effects in female fertility using real and simulated data from Danish Holstein cattle.

ABSTRACT: Exploring dominance variance and loci contributing to dominance variation is important to understand the genetic architecture behind quantitative traits. The objectives of this study were i) to estimate dominance variances, ii) to detect quantitative trait loci (QTL) with dominant effects, and iii) to evaluate the power and the precision of identifying loci with dominance effect through post-hoc simulations, with applications for female fertility in Danish Holstein cattle. The female fertility records analyzed were number of inseminations (NINS), days from calving to first insemination (ICF), and days from the first to last insemination (IFL), covering both abilities to recycle and to get pregnant in the female reproductive cycle. There were 3,040 heifers and 4,483 cows with both female fe

SUBMITTER: Mao X 

PROVIDER: S-EPMC7031268 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature