Intrinsic neuronal properties represent song and error in zebra finch vocal learning.

ABSTRACT: Neurons regulate their intrinsic physiological properties, which could influence network properties and contribute to behavioral plasticity. Recording from adult zebra finch brain slices we show that within each bird basal ganglia Area X-projecting (HVC_X) neurons share similar spike waveform morphology and timing of spike trains, with modeling indicating similar magnitudes of five principal ion currents. These properties vary among birds in lawful relation to acoustic similarity of the birds' songs, with adult sibling pairs (same songs) sharing similar waveforms and spiking characteristics. The properties are maintained dynamically: HVC_X within juveniles learning to sing show variable properties, whereas the uniformity rapidly degrades within hours in adults singing w

SUBMITTER: Daou A 

PROVIDER: S-EPMC7031510 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature