Gut microbiota and obesity: Impact of antibiotics and prebiotics and potential for musculoskeletal health.

ABSTRACT: Obesity is a complex disease with multiple contributing factors. One of the most intensely studied factors during the past decade has been the gut microbiota, which is the community of all microbes in the intestinal tract. The gut microbiota, via energy extraction, inflammation, and other actions, is now recognized as an important player in the pathogenesis of obesity. Dysbiosis, or an imbalance in the microbial community, can initiate a cascade of metabolic disturbances in the host. Early life is a particularly important period for the development of the gut microbiota, and perturbations such as with antibiotic exposure can have long-lasting consequences for host health. In early life and throughout the life span, diet is one of the most important factors that shape the gut microbiota. Al

SUBMITTER: Klancic T 

PROVIDER: S-EPMC7031774 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature