Adverse events in Chinese human immunodeficiency virus (HIV) patients receiving first line antiretroviral therapy.

ABSTRACT:

Background

Although the global human immunodeficiency virus (HIV) epidemic has improved significantly due to antiretroviral treatment (ART), ART-related adverse events (AEs) remain an issue. Therefore, investigating the factors associated with ART-related AEs may provide vital information for monitoring risks.

Methods

A prospective cohort study was conducted among adult patients (aged 18 years or older) with HIV who received Tenofovir (TDF) + Lamivudine (3TC) + Efavirenz (EFV) as first-line ART regimens. All AEs during the first 12 months of therapy were recorded. Logistic regression analysis was used to identify variables associated with AEs.

Results

Four hundred seventy-four patients receiving TDF+ 3TC+ EFV ART regimens between March 2017 and October 2017 were inclu

SUBMITTER: Dai L 

PROVIDER: S-EPMC7031902 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature