Increased Dose and Duration of Statin Use Is Associated with Decreased Asthma-Related Emergency Department Visits and Hospitalizations.

ABSTRACT: BACKGROUND:Statins have pleiotropic anti-inflammatory and immunomodulatory effects, yet the effect of statin use on asthma-related emergency department (ED) visits and hospitalizations has remained unclear, especially in Asian populations. OBJECTIVE:We sought to examine the effect of statin therapy on asthma-related ED visits and/or hospitalizations. METHODS:A cohort study was conducted using data from Taiwan's National Health Insurance Research Database from 2001 to 2013. A total of 117,595 adult patients with asthma were included. The outcomes were defined as asthma-related ED visits and/or hospitalizations. Multiple Cox proportional hazards models were applied to determine the effect of statin use on asthma-related ED visits and/or hospitalizations. RESULTS:There were 3,417 asthma-relat

SUBMITTER: Wang JY 

PROVIDER: S-EPMC7032037 | biostudies-literature | 2018 Sep - Oct

REPOSITORIES: biostudies-literature