Use of seed gums from Tamarindus indica and Cassia fistula as controlled-release agents.

ABSTRACT: Most seed gums have been widely used in oral and topical pharmaceutical formulations, cosmetics, and food products because of their hydrophilic properties. Gums from Tamariudus indica and Cassia fistula seeds were chemically modified by carboxymethylation to improve their functionalities. The objective of the present study was to characterize and evaluate crude and carboxymethylated gums from T. indica and C. fistula seeds to achieve the controlled-release of diclofenac sodium (DS) in matrix tablet form. Both crude and carboxymethylated gums were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, and scanning electron microscopy. The results revealed that the gums were successfully modified by carboxymethylation and that the modified gu

SUBMITTER: Huanbutta K 

PROVIDER: S-EPMC7032240 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature