A prognostic model to personalize monitoring regimes for patients with incidental asymptomatic meningiomas.

ABSTRACT:

Background

Asymptomatic meningioma is a common incidental finding with no consensus on the optimal management strategy. We aimed to develop a prognostic model to guide personalized monitoring of incidental meningioma patients.

Methods

A prognostic model of disease progression was developed in a retrospective cohort (2007-2015), defined as: symptom development, meningioma-specific mortality, meningioma growth or loss of window of curability. Secondary endpoints included non-meningioma-specific mortality and intervention.

Results

Included were 441 patients (459 meningiomas). Over a median of 55 months (interquartile range, 37-80), 44 patients had meningioma progression and 57 died (non-meningioma-specific). Forty-four had intervention (at presentation, n = 6; progressio

SUBMITTER: Islim AI 

PROVIDER: S-EPMC7032634 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature