Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI.

ABSTRACT:

Background

The causative agents for the current national outbreak of electronic-cigarette, or vaping, product use-associated lung injury (EVALI) have not been established. Detection of toxicants in bronchoalveolar-lavage (BAL) fluid from patients with EVALI can provide direct information on exposure within the lung.

Methods

BAL fluids were collected from 51 patients with EVALI in 16 states and from 99 healthy participants who were part of an ongoing study of smoking involving nonsmokers, exclusive users of e-cigarettes or vaping products, and exclusive cigarette smokers that was initiated in 2015. Using the BAL fluid, we performed isotope dilution mass spectrometry to measure several priority toxicants: vitamin E acetate, plant oils, medium-chain triglyceride oil, coconut oi

SUBMITTER: Blount BC 

PROVIDER: S-EPMC7032996 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature