The repeatability of bilateral diffusion tensor imaging (DTI) in the upper leg muscles of healthy adults.

ABSTRACT:

Objectives

Assessment of the repeatability of diffusion parameter estimations in the upper leg muscles of healthy adults over the time course of 2 weeks, from a simultaneous bilateral upper leg DTI measurement.

Methods

SE-EPI DTI datasets were acquired at 3 T in the upper legs of 15 active adults at a time interval of 2 weeks. ROIs were manually drawn for four quadriceps and three hamstring muscles of both legs. The following DTI parameters were analyzed: 1st, 2nd, and 3rd eigenvalue (λ₁, λ₂, and λ₃), mean diffusivity (MD), and fractional anisotropy (FA). DTI parameters per muscle were calculated with and without intravoxel incoherent motion (IVIM) correction together with SNR levels per muscle. Bland-Altman plots and within-subject coefficie

SUBMITTER: Monte JR 

PROVIDER: S-EPMC7033061 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature