Associations between life-course-persistent antisocial behaviour and brain structure in a population-representative longitudinal birth cohort.

ABSTRACT:

Background

Studies with behavioural and neuropsychological tests have supported the developmental taxonomy theory of antisocial behaviour, which specifies abnormal brain development as a fundamental aspect of life-course-persistent antisocial behaviour, but no study has characterised features of brain structure associated with life-course-persistent versus adolescence-limited trajectories, as defined by prospective data. We aimed to determine whether life-course-persistent antisocial behaviour is associated with neurocognitive abnormalities by testing the hypothesis that it is also associated with brain structure abnormalities.

Methods

We used structural MRI data collected at 45 years of age from participants in the Dunedin Study, a population-representative longitudinal bir

SUBMITTER: Carlisi CO 

PROVIDER: S-EPMC7033555 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature