A Wireless Pressure Sensor for Continuous Monitoring of Intraocular Pressure in Conscious Animals.

ABSTRACT: An important aspect of eye health in humans and animal models of human diseases is intraocular pressure (IOP). IOP is typically measured by hand with a tonometer, so data are sparse and sporadic and round-the-clock variations are not well characterized. Here we present a novel system for continuous wireless IOP and temperature measurement in small animals. The system consists of a cannula implanted in the anterior chamber of the eye connected to pressure sensing electronics that can be worn by rats or implanted in larger mammals. The system can record IOP with 0.3 mmHg accuracy and negligible drift at a rate of 0.25 Hz for 1-2 months on a regulated battery or indefinitely at rates up to 250 Hz via RF energy harvesting. Chronic recordings from conscious rats showed that IOP follows a diurna

SUBMITTER: Bello SA 

PROVIDER: S-EPMC7034622 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature