A pilot study on efficacy and safety of a new salt substitute with very low sodium among hypertension patients on regular treatment.

ABSTRACT:

Objectives

To understand the possible effect of a novel salt substitute with very low sodium in reducing blood pressure, salt intake and use of anti-hypertensive medications among patients on regular medications, to inform the future randomized trials.

Design

Single-arm pilot trial.

Setting

A community health service center in Chongqing, China.

Participants

A total of 43 patients with hypertension taking anti-hypertensive medications regularly.

Intervention

Patients received the salt substitute with 18% sodium chloride for 8 weeks.

Main outcome measures

Patients were followed up weekly for the use of antihypertensive medications and measurements of blood pressure. We collected 24-h urine before and after the trial to measure sodium and potassium i

SUBMITTER: Mu L 

PROVIDER: S-EPMC7034699 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature