Attributable burden in patients with carbapenem-nonsusceptible gram-negative respiratory infections.

ABSTRACT: OBJECTIVE:We aimed to describe the clinical and economic burden attributable to carbapenem-nonsusceptible (C-NS) respiratory infections. METHODS:This retrospective matched cohort study assessed clinical and economic outcomes of adult patients (aged ≥18 years) who were admitted to one of 78 acute care hospitals in the United States with nonduplicate C-NS and carbapenem-susceptible (C-S) isolates from a respiratory source. A subset analysis of patients with principal diagnosis codes denoting bacterial pneumonia or other diagnoses was also conducted. Isolates were classified as community- or hospital-onset based on collection time. A generalized linear mixed model method was used to estimate the attributable burden for mortality, 30-day readmission, length of stay (LOS), cost, and net gain/lo

SUBMITTER: Tabak YP 

PROVIDER: S-EPMC7034906 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature