Integrative and Network-Specific Connectivity of the Basal Ganglia and Thalamus Defined in Individuals.

ABSTRACT: The basal ganglia, thalamus, and cerebral cortex form an interconnected network implicated in many neurological and psychiatric illnesses. A better understanding of cortico-subcortical circuits in individuals will aid in development of personalized treatments. Using precision functional mapping-individual-specific analysis of highly sampled human participants-we investigated individual-specific functional connectivity between subcortical structures and cortical functional networks. This approach revealed distinct subcortical zones of network specificity and multi-network integration. Integration zones were systematic, with convergence of cingulo-opercular control and somatomotor networks in the ventral intermediate thalamus (motor integration zones), dorsal attention and visual networks in

SUBMITTER: Greene DJ 

PROVIDER: S-EPMC7035165 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature