In-vivo vascular application via ultra-fast bioprinting for future 5D personalised nanomedicine.

ABSTRACT: The design of 3D complex structures enables new correlation studies between the engineering parameters and the biological activity. Moreover, additive manufacturing technology could revolutionise the personalised medical pre-operative management due to its possibility to interplay with computer tomography. Here we present a method based on rapid freeze prototyping (RFP) 3D printer, reconstruction cutting, nano dry formulation, fast freeze gelation, disinfection and partial processes for the 5D digital models functionalisation. We elaborated the high-resolution computer tomography scan derived from a complex human peripheral artery and we reconstructed the 3D model of the vessel in order to obtain and verify the additive manufacturing processes. Then, based on the drug-eluting balloon selec

SUBMITTER: Foresti R 

PROVIDER: S-EPMC7035336 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature