Clinical and laboratory features associated with serum phosphate concentrations in malaria and other febrile illnesses.

ABSTRACT:

Background

Hypophosphatemia is common in severe infections including malaria. Previous studies suggested that serum phosphate concentrations correlate with temperature, but it is unclear whether the type of infection and other factors occurring during infection influence this association. Here relationships were investigated between serum phosphate levels, cause of fever, demographic, clinical and laboratory parameters.

Methods

Anonymized data were analysed from 633 adults with malaria or other febrile illness admitted to Northwick Park Hospital, London, UK. Univariable and multivariable generalized linear model analyses were performed to examine associations with serum phosphate levels. Interaction terms were included to investigate whether cause of fever (malaria vs other

SUBMITTER: Suen HE 

PROVIDER: S-EPMC7035648 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature