Patterns of Arterial Disease in Takayasu Arteritis and Giant Cell Arteritis.

ABSTRACT:

Objective

To identify and validate, using computer-driven methods, patterns of arterial disease in Takayasu arteritis (TAK) and giant cell arteritis (GCA).

Methods

Patients with TAK or GCA were studied from the Diagnostic and Classification Criteria for Vasculitis (DCVAS) cohort and a combined North American cohort. Case inclusion required evidence of large-vessel involvement, defined as stenosis, occlusion, or aneurysm by angiography/ultrasonography, or increased ¹⁸ F-fluorodeoxyglucose (FDG) uptake by positron emission tomography (PET) in at least 1 of 11 specified arterial territories. K-means cluster analysis identified groups of patients based on the pattern of arterial involvement. Cluster groups were identified in the DCVAS cohort and independently validate

SUBMITTER: Gribbons KB 

PROVIDER: S-EPMC7035996 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature