Reduced parietal alpha power and psychotic symptoms: Test-retest reliability of resting-state magnetoencephalography in schizophrenia and healthy controls.

ABSTRACT:

Background

Despite increased reporting of resting-state magnetoencephalography (MEG), reliability of those measures remains scarce and predominately reported in healthy controls (HC). As such, there is limited knowledge on MEG resting-state reliability in schizophrenia (SZ).

Methods

To address test-retest reliability in psychosis, a reproducibility study of 26 participants (13-SZ, 13-HC) was performed. We collected eyes open and eyes closed resting-state data during 4 separate instances (2 Visits, 2 runs per visit) to estimate spectral power reliability (power, normalized power, alpha reactivity) across one hour and one week. Intraclass correlation coefficients (ICCs) were calculated. For source modeling, we applied an anatomically constrained linear estimation inverse model

SUBMITTER: Candelaria-Cook FT 

PROVIDER: S-EPMC7036030 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature