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Biodegradation of penicillin G from industrial bacteria residue by immobilized cells of Paracoccus sp. KDSPL-02 through continuous expanded bed adsorption bioreactor.

ABSTRACT:

Background

An efficient biodegradation-strengthening approach was developed to improve penicillin G degradation from industrial bacterial residue in an expanded bed adsorption bioreactor (EBAB) is reported in this paper.

Results

Paracoccus sp. strain KDSPL-02 was isolated based on its ability to use penicillin G as the sole carbon and nitrogen source. Strain identification was based on analyses of morphology, physio-biochemical characteristics, and 16S rDNA sequences. The effects of temperature, pH, PVA-sodium alginate concentration, calcium chloride concentration and initial penicillin G concentration were investigated. Repeated operations of immobilized cells with EBAB, At initial penicillin concentrations below 2.0 g L^- 1, the continuous mode could reach more than 20 times, and the degradation rate reached 100%.

Conclusions

The present study suggests that the EBAB system can be utilized for the simple and economical biodegradation of penicillin G from industrial bacterial residue.

SUBMITTER: Wang P

PROVIDER: S-EPMC7036172 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Biodegradation of penicillin G from industrial bacteria residue by immobilized cells of <i>Paracoccus</i> sp. KDSPL-02 through continuous expanded bed adsorption bioreactor.

Wang Peng P Shen Chen C Wang Xiaochun X Liu Shouxin S Li Luwei L Guo Jinfeng J

Journal of biological engineering 20200222

<h4>Background</h4>An efficient biodegradation-strengthening approach was developed to improve penicillin G degradation from industrial bacterial residue in an expanded bed adsorption bioreactor (EBAB) is reported in this paper.<h4>Results</h4><i>Paracoccus</i> sp. strain KDSPL-02 was isolated based on its ability to use penicillin G as the sole carbon and nitrogen source. Strain identification was based on analyses of morphology, physio-biochemical characteristics, and 16S rDNA sequences. The e ...[more]

PMID: 32123541

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