Combined Effects of Diatom-Derived Oxylipins on the Sea Urchin Paracentrotus lividus.

ABSTRACT: Oxylipins are diatom-derived secondary metabolites, deriving from the oxidation of polyunsatured fatty acids that are released from cell membranes after cell damage or senescence of these single-celled algae. Previous results revealed harmful toxic effects of polyunsaturated aldehydes (PUAs) and hydroxyacids (HEPEs) on sea urchin Paracentrotus lividus embryonic development by testing individual compounds and mixtures of the same chemical group. Here, we investigated the combined effects of these compounds on sea urchin development at the morphological and molecular level for the first time. Our results demonstrated that oxylipin mixtures had stronger effects on sea urchin embryos compared with individual compounds, confirming that PUAs induce malformations and HEPEs cause developmen

SUBMITTER: Esposito R 

PROVIDER: S-EPMC7036778 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature