Exhaled Breath Analysis in Diagnosis of Malignant Pleural Mesothelioma: Systematic Review.

ABSTRACT: Malignant pleural mesothelioma (MPM) is mainly related to previous asbestos exposure. There is still dearth of information on non-invasive biomarkers to detect MPM at early stages. Human studies on exhaled breath biomarkers of cancer and asbestos-related diseases show encouraging results. The aim of this systematic review was to provide an overview on the current knowledge about exhaled breath analysis in MPM diagnosis. A systematic review was conducted on MEDLINE (PubMed), EMBASE and Web of Science databases to identify relevant studies. Quality assessment was done by the Newcastle-Ottawa Scale. Six studies were identified, all of which showed fair quality and explored volatile organic compounds (VOC) based breath profile using Gas Chromatography Coupled to Mass Spectrometry (GC-MS), Ion

SUBMITTER: Toreyin ZN 

PROVIDER: S-EPMC7036862 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature