Understanding the Solution Behavior of Epinephrine in the Presence of Toxic Cations: A Thermodynamic Investigation in Different Experimental Conditions.

ABSTRACT: The interactions of epinephrine ((R)-(-)-3,4-dihydroxy-α-(methylaminomethyl)benzyl alcohol; Eph^-) with different toxic cations (methylmercury(II): CH₃Hg⁺; dimethyltin(IV): (CH₃)₂Sn²⁺; dioxouranium(VI): UO₂²⁺) were studied in NaCl_aq at different ionic strengths and at T = 298.15 K (T = 310.15 K for (CH₃)₂Sn²⁺). The enthalpy changes for the protonation of epinephrine and its complex formation with UO₂²⁺ were also determined using isoperibolic titration calorimetry: H_HL = -39 ± 1 kJ mol^-1, H_H2L = -67 ± 1 kJ mol^-1 (overall reaction), H_ML =

SUBMITTER: Crea F 

PROVIDER: S-EPMC7037007 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature