A pilot study on the relation between irisin single-nucleotide polymorphism and risk of myocardial infarction.

ABSTRACT:

Background

Myocardial infarction (MI) is the major cause of death and disability worldwide. Many recent studies revealed the relationship between circulating irisin levels, endothelial dysfunctions and subclinical atherosclerosis in adult patients.

Objectives

The aim of this study was to investigate the distribution of Irisin gene single nucleotide polymorphism in patients with MI and its association with other clinical and laboratory variables in these patients.

Patients and methods

This study was carried out in 100 patients with MI, and 100 healthy subjects served as controls. All studied subjects underwent laboratory investigations, including measurement of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-c) high-density l

SUBMITTER: Badr EA 

PROVIDER: S-EPMC7038008 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature