More random motor activity fluctuations predict incident frailty, disability, and mortality.

ABSTRACT: Mobile healthcare increasingly relies on analytical tools that can extract meaningful information from ambulatory physiological recordings. We tested whether a nonlinear tool of fractal physiology could predict long-term health consequences in a large, elderly cohort. Fractal physiology is an emerging field that aims to study how fractal temporal structures in physiological fluctuations generated by complex physiological networks can provide important information about system adaptability. We assessed fractal temporal correlations in the spontaneous fluctuations of ambulatory motor activity of 1275 older participants at baseline, with a follow-up period of up to 13 years. We found that people with reduced temporal correlations (more random activity fluctuations) at baseline had increased r

SUBMITTER: Li P 

PROVIDER: S-EPMC7038816 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature