The practicality of different eGFR equations in centenarians and near-centenarians: which equation should we choose?

ABSTRACT:

Background

No studies have examined the practicality of the Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiological Collaboration (CKD-EPI) and Berlin Initiative Study 1 (BIS1) equations for the estimated glomerular filtration rate (eGFR) in a large sample of centenarians. We aim to investigate the differences among the equations and suggest the most suitable equation for centenarians and near-centenarians.

Methods

A total of 966 centenarians and 787 near-centenarians were enrolled, and the eGFR was calculated using the three equations mentioned above. Agreement among the equations was investigated with the κ statistic and Bland-Altman plots. Sources of discrepancy were investigated using a partial correlation analysis.

Results

The

SUBMITTER: Han Q 

PROVIDER: S-EPMC7039118 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature