Optimal Hemodynamics During Left Ventricular Assist Device Support Are Associated With Reduced Readmission Rates.

ABSTRACT:

Background

Left ventricular assist device (LVAD) therapy improves the hemodynamics of advanced heart failure patients. However, it is unknown whether hemodynamic optimization improves clinical outcomes. The aim of this study was to investigate whether hemodynamic optimization reduces hospital readmission rate in LVAD patients.

Methods and results

LVAD patients undergoing an invasive hemodynamic ramp test were prospectively enrolled and followed for 1 year. LVAD speed was optimized using a ramp test, targeting the following goals: central venous pressure <12 mm Hg, pulmonary capillary wedge pressure <18 mm Hg, and cardiac index >2.2 L/(min·m²). The frequency and cause of hospital readmissions were compared between patients who achieved (optimized group) or did not

SUBMITTER: Imamura T 

PROVIDER: S-EPMC7039343 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature