Testis transcriptome profiling identified genes involved in spermatogenic arrest of cattleyak.

ABSTRACT:

Background

Cattleyak are the hybrid offspring between cattle and yak and combine yak hardiness with cattle productivity. Much attempt has been made to examine the mechanisms of male sterility caused by spermatogenic arrest, but yet there is no research systematically and precisely elucidated testis gene expression profiling between cattleyak and yak.

Methods

To explore the higher resolution comparative transcriptome map between the testes of yak and cattleyak, and further analyze the mRNA expression dynamics of spermatogenic arrest in cattleyak. We characterized the comparative transcriptome profile from the testes of yak and cattleyak using high-throughput sequencing. Then we used quantitative analysis to validate several differentially expressed genes (DEGs) in testicular

SUBMITTER: Wu S 

PROVIDER: S-EPMC7039509 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature